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Posts Tagged ‘PREVENTION’

Preventing unintended pregnancy






In this large prospective cohort study, women who received free contraception had lower rates of abortion, repeat abortion, and teenage births compared to their regional and national peers. [ABSTRACT FROM AUTHOR]


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Gas-free beans and green coffee bean extract

The article presents questions and answers on how beans can be made gas free and what are the health benefits on green coffee bean extract.

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Early lessons learned from extramural school programs that offer hpv vaccine

BACKGROUND There has been little evaluation of school-located vaccination programs that offer human papillomavirus (HPV) vaccine in US schools without health centers (ie, extramural programs). This article summarizes lessons learned from such programs. METHODS In July to August 2010, 5 programs were identified. Semistructured, in-depth telephone interviews were conducted with program representatives about practical aspects of planning and implementation, including configuration and effectiveness. RESULTS Most programs offered HPV vaccine as part of a broader effort to increase uptake of adolescent vaccines. Respondents stressed the importance of building partnerships with local school systems throughout all aspects of the planning and implementation phases. All programs offered HPV vaccine at no cost to students. Most did not have a mechanism to bill private insurance, and some found Medicaid reimbursements to be a challenge. Programs achieved modest rates of initiation of the 3-dose HPV vaccine series (median 10%); however, among those who initiated the series, completion rates were high (median 78%). HPV vaccine uptake was lowest for a program that offered only HPV vaccine. CONCLUSIONS Extramural programs may increase uptake of vaccines and decrease absenteeism due to noncompliance with vaccine requirements for school entry. Until extramural programs in the US receive better access to billing private insurers and Medicaid, sustainability of these programs relies on grant funding. Better integration of extramural school-located vaccine programs with existing local healthcare and other programs at schools is an area for growth. [ABSTRACT FROM AUTHOR]

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Salt, we misjudged you

Oakland, Calif. THE first time I questioned the conventional wisdom on the nature of a healthy diet, I was in my salad days, almost 40 years ago, and the subject was salt. Researchers were claiming that salt supplementation was unnecessary after strenuous exercise, and this advice was being passed on by health reporters. All I knew was that I had played high school football in suburban Maryland, sweating profusely through double sessions in the swamplike 90-degree days of August. Without salt pills, I couldn’t make it through a two-hour practice; I couldn’t walk across the parking lot afterward without cramping.

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Macmillan puts its green foot forward

The article discusses the environmental efforts of publishing company Macmillan in 2012, focusing on the company’s chief executive officer (CEO) John Sargent and his plans to lower Macmillan’s carbon footprint. Sargent’s plan for reducing Macmillan’s carbon emissions from paper usage involves making changes to its source paper, including a lowering of the basis weight of the paper used.

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The silent killers

The article looks at military policies by the administration of U.S. President Barack Obama as of June 2012. Topics include the U.S. Central Intelligence Agency’s (CIA) procedure for issuing drone missile strikes by unmanned aircraft in the Middle East, the concept of signature strikes, also known as crowd killing, and the roles of James Cartwright, vice chairman of the Joint Chiefs of Staff, and John Brennan, Obama’s counterterrorism aide, in shaping Obama’s military tactics.

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The albanian legal framework on non-discrimination and gender equality in employment relationships

Discrimination and gender inequality in employment relationships are present in every society, at any time and whatever their victim is. With the development of society, despite the measures taken to prevent discrimination, this phenomenon continues to be present and appears in different forms. In a society with economic civilization and culture development, people cannot explain why do such phenomena that become an obstacle to the realization of a right as the right to employment exist, when it is sanctioned and guaranteed by the Constitution of the Republic of Albania, in international conventions ratified by our country, in the Labor Code and particular laws, such as the “Gender Equality law”. Discrimination in employment relationships and in the workplace continues to appear in its traditional format based on gender, race, ethnic origin, religion, age but also in new forms based on disability, sexual orientation, genetics and lifestyle. Despite all efforts to prevent discrimination, this phenomenon has always been a threat to all individuals seeking to enter into an employment relationship. We all have the right to work, to be treated equally during a competition for a particular job, to get a fair wage, to be paid equally with others for the same job, to get promotion, to be safety in work, to get vocational training and retraining benefits without being discriminated of race, religion, age, gender, political belief, sexual orientation, etc. However, the first opportunity for discrimination is encountered from the moment when hiring an individual. But, despite the momentum when we are faced with discrimination or one of its kind, there should be placed great attention by the State through the relevant authorities and by the society itself by denouncing it. We shouldn’t be subject of violation of the right to employment and equal treatment in employment relations. Not without reason the two principles: the principle of prohibition of discrimination and gender equality are two principles enshrined in international conventions, giving it a great importance. In this paper there is addressed the Albanian legal framework that sanctioned and guaranteed the principles of prohibition of discrimination and gender equality, as the Constitution of the Republic of Albania, the Labor Code, the law on “Gender Equality in Albania”, as well as institutional mechanisms to ensure gender equality in Albania. [ABSTRACT FROM AUTHOR]

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Concerns regarding the use of dabigatran for stroke prevention in atrial fibrillation

Dabigatran is an oral thrombin inhibitor which has been approved in several countries as an alternative to vitamin-K-antagonists for the prevention of stroke or embolism in atrial fibrillation patients. Dabigatran is introduced into clinical practice, although many issues regarding this drug are still unclear, like laboratory monitoring, use in elderly patients, drug- and food-interactions and use in patients with renal insufficiency. Additionally, there is no antidote for dabigatran. Thus, aim of the present review is to give an overview of concerns and unresolved issues concerning dabigatran. [ABSTRACT FROM AUTHOR]

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Human embryo pancreatic stem cells differentiating into active insulin secreting islet-like structure

±Background: Prevalence rate of diabetes is increasing dramatically these years and it has become one major disease threatening people’s health. Pancreatic islet transplantation is the most effective treatment to cure the insulin dependent diabetes. While deficiency of the pancreas donators limit the clinical application of islet transplantation. Stem cells have the potency to self-renewal and differentiate into all kinds of tissue cells. Objective: To establish a method that induced islet cells differentiated from pancreatic stem cells to form the islet-like structures in vitro. Methods: Inducing human fetal pancreatic stem cells differentiating into the islet cells in vitro, and the islet cells were suspended in medium containing extra-cellular matrix (ECM) and cultured for 24 h to induce the formation of the islet-like structures. The morphology and size of the islet-like structures were detected under fluorescence stereomicroscope; the ECM components and cellular types and location in the islet-like structures were detected by immunofluorescence staining. The islet-like structures and the insulin release levels in the supernatant were detected by radioimmunoassay. Rat models of diabetes where established, and transplanting the islet-like structures into the liver of rats through the portal vein, detecting the glucose levels for 3 days through the tail vein of rats. Results: 90% of islet cells differentiated from human fetal pancreatic were aggregated spontaneously into the islet-like structures, which displayed obvious integrity outer membrane and similar size with native human islets. Using the diameter of 150 µm as a standard, the relationship between cells concentration and the formation rates of the islet-like structures was analyzed, and the result showed that the formation rate of the islet-like structures in the 1 x 105 /ml group (36.5% 4.0%, P < 0.01) was best compared to others. The insulin release levels of the islet-like structures induced by 30.0 mmol/L glucose (110 µIU/ml ± 12 µIU/ ml, P < 0.01) increased significantly compared with 5.6 mmol/L glucose (59.5 µIU/ml ± 8.0 µIU/ ml), and the glucose levels in diabetes rats decreased significantly after the islet-like structures transplantation (P < 0.01). Conclusion: Islet cells differentiated from pancreatic stem cells could be induced to form functional islet-like structures largely and quickly by the established method in vitro. [ABSTRACT FROM AUTHOR]

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Risk evaluation and mitigation strategies: assessment of a medical center’s policies and procedures

Purpose. The results of a hospital’s initiative to evaluate and improve compliance with federally mandated risk evaluation and mitigation strategies (REMS) are presented. Summary. Food and Drug Administration approved REMS plans are required for more than 145 drugs, but clear guidance on strategies for achieving REMS compliance is lacking. As a first step toward determining the extent of REMS compliance at a large medical center, a systematic assessment was conducted to ascertain existing policies and procedures for the use of drugs subject to REMS requirements applicable in the inpatient setting. About 123 drugs with such “inpatient-applicable” REMS requirements were identified; of those, 10 had been ordered by hospital providers during a specified 18-month time frame and were included in the assessment of policies and procedures. The assessment revealed that the hospital lacked a formal REMS policy and had no REMS-compliant procedures in place for 7 evaluated drugs (ambrisentan, buprenorphine-naloxone, darbepoetin alfa, epoetin alfa, oxycodone controlled-release tablets, prasugrel, and pregabalin). Pursuant to the compliance assessment, new procedures to help ensure the safe use of those 7 drugs were developed, and REMS-focused educational programs, order-entry system enhancements, and drug storage modifications were implemented. Conclusion. Quality-improvement initiatives including staff education, incorporation of REMS requirements into existing policy, development of an electronic resource, and creation of a separate storage section for drugs subject to REMS were implemented at a large academic medical center to help ensure compliance with inpatient-applicable REMS requirements. [ABSTRACT FROM AUTHOR]

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